MaxQuant
A quantitative proteomics software package.
Overview
MaxQuant is a quantitative proteomics software package designed for analyzing large mass-spectrometric data sets. It is specifically aimed at high-resolution MS data and supports all main labeling techniques, like SILAC and iTRAQ/TMT, as well as label-free quantification. It is one of the most widely used platforms for proteomics data analysis in academia.
✨ Key Features
- Label-free quantification (MaxLFQ algorithm)
- Support for SILAC, TMT, and iTRAQ quantification
- Andromeda search engine for peptide identification
- Statistical analysis and visualization (in Perseus)
- Feature detection and alignment across multiple runs
- False Discovery Rate (FDR) control
🎯 Key Differentiators
- Completely free for academic and commercial use.
- Highly accurate and robust label-free quantification (MaxLFQ).
- Optimized for high-resolution Orbitrap data.
Unique Value: Provides a powerful, validated, and completely free platform for state-of-the-art quantitative proteomics analysis.
🎯 Use Cases (4)
✅ Best For
- One of the most highly cited software packages in the proteomics field.
- The MaxLFQ algorithm is a benchmark for label-free quantification.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- De novo sequencing
- Biopharmaceutical characterization (requires more specialized tools)
- Users requiring a graphical workflow builder
🏆 Alternatives
Offers performance comparable to or exceeding commercial software for many quantitative tasks, at no cost.
💻 Platforms
✅ Offline Mode Available
🔌 Integrations
💰 Pricing
Free tier: Fully functional and free for everyone.
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